In contrast, Ca2+ levels of 0
In contrast, Ca2+ levels of 0.1mM caused inhibition of PAF-CPT in the absence of EDTA ( .05), which Paeoniflorin was partially reduced by the presence of the chelate reagent. Table 2 Effect of Mg2+ cation on PAF-CPT activity of HMC. to 1-pathway the final step includes an acetylation of l-alkyl-2-lyso-pathway should mainly contribute to PAF synthesis for maintaining its basal levels under physiological conditions, whereas the pathway should be more involved in the production Paeoniflorin of PAF during inflammatory responses [7, 8]. However, the information collected so far concerning PAF biosynthetic pathways suggest that the contribution of the aforementioned enzymes to PAF synthesis depends on several factors under physiological and pathological conditions [8C13], and so the above point of view should be reevaluated and further studied. The important regulatory enzyme…