Data from circulation ELISA and cytometry IgG reactions with background subtracted are indicated, and consultant stream cytometry plots are shown in statistics in the primary Supplementary and text message Figs
Data from circulation ELISA and cytometry IgG reactions with background subtracted are indicated, and consultant stream cytometry plots are shown in statistics in the primary Supplementary and text message Figs. (B) vaccines differ significantly in their capability to elicit neutralizing antibodies but possess somewhat comparable efficiency in safeguarding from serious COVID-19. We executed further analyses for the randomized trial (Cobovax research, NCT05057169) of third dosage homologous and heterologous booster vaccination, i.e. four interventions CC-C, CC-B, BB-B and BB-C. Right here, we assess vaccine immunogenicity beyond neutralizing function, including S and non-S antibodies with Fc receptor (FcR) binding, antibody T and avidity cell specificity to six months post-vaccination. Ancestral and Omicron S-specific IgG and FcR binding are higher by BNT162b2 booster than CoronaVac considerably, of first doses regardless. Nucleocapsid (N) antibodies…